THE 5th YEAR RESIDENTS ARE TESTED IN THEIR FIRST SOLO SURGERIES, ON ABC'S "GREY'S ANATOMY"

"Take the Lead" - The Chief makes a career-changing decision that shocks Seattle Grace Hospital; Cristina and Owen try to find normalcy in their relationship; April continues to struggle in her new role; and the 5th year residents are given their first solo surgeries, only to find out that even the most routine procedures aren't always easy, on Grey's Anatomy, THURSDAY, SEPTEMBER 29 (9:00-10:02 p.m., ET) on the ABC Television Network.

"Grey's Anatomy" stars Ellen Pompeo as Meredith Grey, Patrick Dempsey as Derek Shepherd, Sandra Oh as Cristina Yang, Justin Chambers as Alex Karev, Chandra Wilson as Miranda Bailey, James Pickens, Jr. as Richard Webber, Sara Ramirez as Callie Torres, Eric Dane as Mark Sloan, Chyler Leigh as Lexie Grey, Kevin McKidd as Owen Hunt, Jessica Capshaw as Arizona Robbins, Kim Raver as Teddy Altman, Jesse Williams as Jackson Avery and Sarah Drew as April Kepner.

Guest cast TBA.

"Take the Lead" was written by William Harper and directed by Chandra Wilson.

"Grey's Anatomy" is broadcasted in 720 Progressive (720P), ABC's selected HTV format, with 5.1-channel surround sound. A TV parental guideline will be assigned closer to airdate.

For more information on "Grey's Anatomy" please visit ABC.com.