"EXTREME MAKEOVER: HOME EDITION" BUILDS A NEW HOME FOR A FAMILY WHOSE SON WORKS TO HELP GRANT WISHES FOR OTHER CHILDREN WHILE BATTLING HIS OWN RARE AND LIFE-THREATENING DISEASE

Sheryl Crow, Miranda Lambert, Sarah McLachlan Appear in Episode; Make-a-Wish Foundation Also Helps Fulfill This Family's Ultimate Wish

"Starkweather Family" - In this special story for Mother's Day, "Extreme Makeover: Home Edition" travels to Tulsa, OK to meet Toen and Amy Starkweather, whose ten-year-old son, Ethan, suffers from a rare disorder called Prader-Willi syndrome. This incurable disease causes low muscle tone, labored speech, troubled breathing and a malfunctioning hypothalamus, resulting in extreme and constant hunger. Because Ethan requires 24-hour care, the mounting list of necessary home repairs has continually been on the back burner. The Starkweathers' small home is very old, riddled with foundation, electrical and plumbing problems, and is barely accessible for Ethan. Sheryl Crow and Miranda Lambert are the "Get on the Bus" volunteers working and singing, while Sarah McLachlan also delivers a special message to the family, on "Extreme Makeover: Home Edition," SUNDAY, JULY 25 (8:00-9:00 p.m., ET) on ABC. (Rebroadcast: OAD: 5/9/10)

In light of everything he endures living each day with Prader-Willi, Ethan maintains a remarkably contagious positive attitude. With the help of his parents and older brothers, Jared, 15, and Ryan, 13, Ethan maintains a healthy weight, is in a traditional 4th grade class in school, and is a "poster child" for how a child can progress with this disease. After the national Make-a-Wish foundation granted his wish to visit Walt Disney World, Ethan made it his mission help other Make-a-Wish children with life threatening illnesses reach their goals. As an ambassador for his local Make-a-Wish chapter in Tulsa, he is working to shed light on Prader-Willi syndrome and has also raised thousands of dollars to help grant wishes for other local children. Because Ethan will never be able to live on his own, his current home needs to provide him the things he needs to thrive. Now it's up to the "Extreme Makeover: Home Edition" team to build a new home that will allow Ethan and his family to manage this disease and continue to help others who are living with Prader-Willi syndrome as well.

The Starkweather family will go on vacation a Walt Disney World Resort vacation while "Extreme Makeover: Home Edition" team leader Ty Pennington, designers Paul DiMeo, Eduardo Xol and Paige Hemmis help to rebuild their home. The national Make-a-Wish foundation will also have a special guest on hand, aspiring interior designer Callie London, 11, of Farmington, UT, who suffers from cystic fibrosis. Callie's wish to makeover a kid's room will come to life as she works with Paul DiMeo in designing Ethan's new bedroom.

The series is produced by Endemol USA, a division of Endemol Holding. It is executive-produced by Anthony Dominici. David Goldberg is Chairman, Endemol North America. This program carries a TV-PG parental guideline.

For more information on "Extreme Makeover: Home Edition," visit ABC.com